An increasing number of studies show links between a leaky gut – often caused by SIBO – and conditions such as IBS, chronic inflammation, eczema, fatigue, brain fog, low mood, headaches, sleep disturbances, food intolerances, and metabolic issues.
Since leaky gut and SIBO are well-established risk factors that may contribute to future health problems, it can be valuable to detect and address them as early as possible.
Research has shown that up to 40% of the population may have SIBO without knowing it, and studies link leaky gut to a range of chronic diseases, including:
- Alzheimer’s and Parkinson’s disease
- Multiple sclerosis (MS) and ALS
- Type 2 diabetes and metabolic disorders
- Various forms of autoimmunity.
ImP (imidazole propionate) is a byproduct formed when bacteria in the small intestine break down the amino acid histidine before the body can absorb it. By measuring ImP, we can now give you even better answers in two important areas:
SIBO (small intestinal bacterial overgrowth): ImP reveals whether the wrong bacteria have settled in the wrong place.Metabolic health: Research shows that elevated ImP levels are strongly linked to insulin resistance, abdominal obesity and increased cardiometabolic risk.
Another important factor is TMAO (trimethylamine N-oxide), a substance produced when gut bacteria break down certain foods. Elevated TMAO levels may reflect changes in the gut microbial balance and have been linked in research to low-grade inflammation and various long-term health factors, such as cardiometabolic health, blood sugar regulation, and immune function.